History of Bareilly Essay Example for Free

History of Bareilly Essay The region has, also, acted as a mint for a major part of its history. From archaeological point of view the district of Bareilly is very rich. The extensive remains of Ahichhatra, the Capital town of Northern Panchala have been discovered near Ramnagar village of Aonla Tehsil in the district. It was during the first excavations at Ahichhatra (1940–44) that the painted grey ware, associated with the advent of the Aryans in Ganga Yamuna Valley, was recognised for the first time in the earliest levels of the site. Nearly five thousand coins belonging to periods earlier than that of Guptas have been yielded from Ahichhatra. It has also been one of the richest sites in India from the point of view of the total yield of terracotta. Some of the masterpieces of Indian terracotta art are from Ahichhatra. In fact the classification made of the terracotta human figurines from Ahichhatra on grounds of style and to some extent stratigraphy became a model for determining the stratigraphy of subsequent excavations at other sites in the Ganga Valley. On the basis of the existing material, the archaeology of the region helps us to get an idea of the cultural sequence from the beginning of the 2nd millennium BC up to the 11th c. AD. Some ancient mounds in the district have also been discovered by the Deptt. of Ancient History and culture, Rohilkhand University, at Tihar-Khera (Fatehganj West), Pachaumi, Rahtuia, Kadarganj and Sainthal. [2]

Olivopontocerebellar Atrophy Essay -- Health Medicine Medical Essays

Olivopontocerebellar Atrophy Abstract Olivopontocerebellar Atrophy(OPCA), is characterized by neuronal degeneration of the cerebellar cortex, the inferior olive, and the pons. The symptoms associated with it are primarily cerebellar ataxia with disturbances in equilibrium and gait. However, broader symptomology is usually seen with OPCA. Current research is focusing on three primary systems thought to be responsible for the etiology of OPCA. They are excitatory amino acid disturbances, oligodendroglial microtubular tangles, and phospholipid metabolism disorders. The only treatment for OPCA is therapy focusing on improving the dysphagia associated with the disorder. Olivopontocerebellar Atrophy Olivopontocerebellar Atrophy (OPCA) is a disease characterized primarily by the degeneration of neurons in the cerebellar cortex, pons, and inferior olive. It is a genetic disease, being either autosomal dominant or autosomal recessive in nature. This disorder, which usually occurs in the middle years of life, presents symptoms of cerebellar ataxia, equilibrium disturbance, nystagmus, dysphasia, dysarthria, and possibly intellectual deficits. According to Merritt, the pathology of OPCA includes loss of Purkinje cells, reduction of the number of neurons in the molecular and granular layers of the cerebellum, degeneration of the folia and white matter of the cerebellum, atrophy of the inferior olives and of the olivo-cerebellar connections, and atrophy of the pontine nuclei, arcuate nuclei, and brachium pontis (15). In addition to this, degeneration of the spinocerebellar tracts, corticospinal tracts, and frontal and temporal lobes has been reported (15). Biopsies on living OPCA patients have suggested that there are n... ...cerebellar atrophy. Annals of Neurology, 26:362-367, 1989. 12. Kish, S., Robitaille, Y., El-Awar, M. et. al. Brain amino acid reductions in one family with chromosome 6p-linked dominantly inherited olivopontocerebellar atrophy. Annals of Neurology, 30:780-784, 1991. 13.Landis, D., Rosenburg, R., Landis, S. et. al. Olivopontocerebellar degeneration. Archives of Neurology, 31:295--307, 1974. 14. Makowiec, R., Albin, R., Cha, J-H. et. al. Two types of quisqualate receptors are decreased in human olivopontocerebellar atrophy cerebellar cortex. Brain Research, 523:309-312, 1990. 15. Merritt, Houston. A Textbook of Neurology. Lea and Febiger, Philadelphia. 1967 16. Nakazato, Y., Yamazaki, H., Hirato, J. et. al. Oligodendroglial microtubular tangles in olivopontocerebellar atrophy. Journal of Neuropathology and Experimental Neurology, 49:521-530, 1990. Olivopontocerebellar Atrophy Essay -- Health Medicine Medical Essays Olivopontocerebellar Atrophy Abstract Olivopontocerebellar Atrophy(OPCA), is characterized by neuronal degeneration of the cerebellar cortex, the inferior olive, and the pons. The symptoms associated with it are primarily cerebellar ataxia with disturbances in equilibrium and gait. However, broader symptomology is usually seen with OPCA. Current research is focusing on three primary systems thought to be responsible for the etiology of OPCA. They are excitatory amino acid disturbances, oligodendroglial microtubular tangles, and phospholipid metabolism disorders. The only treatment for OPCA is therapy focusing on improving the dysphagia associated with the disorder. Olivopontocerebellar Atrophy Olivopontocerebellar Atrophy (OPCA) is a disease characterized primarily by the degeneration of neurons in the cerebellar cortex, pons, and inferior olive. It is a genetic disease, being either autosomal dominant or autosomal recessive in nature. This disorder, which usually occurs in the middle years of life, presents symptoms of cerebellar ataxia, equilibrium disturbance, nystagmus, dysphasia, dysarthria, and possibly intellectual deficits. According to Merritt, the pathology of OPCA includes loss of Purkinje cells, reduction of the number of neurons in the molecular and granular layers of the cerebellum, degeneration of the folia and white matter of the cerebellum, atrophy of the inferior olives and of the olivo-cerebellar connections, and atrophy of the pontine nuclei, arcuate nuclei, and brachium pontis (15). In addition to this, degeneration of the spinocerebellar tracts, corticospinal tracts, and frontal and temporal lobes has been reported (15). Biopsies on living OPCA patients have suggested that there are n... ...cerebellar atrophy. Annals of Neurology, 26:362-367, 1989. 12. Kish, S., Robitaille, Y., El-Awar, M. et. al. Brain amino acid reductions in one family with chromosome 6p-linked dominantly inherited olivopontocerebellar atrophy. Annals of Neurology, 30:780-784, 1991. 13.Landis, D., Rosenburg, R., Landis, S. et. al. Olivopontocerebellar degeneration. Archives of Neurology, 31:295--307, 1974. 14. Makowiec, R., Albin, R., Cha, J-H. et. al. Two types of quisqualate receptors are decreased in human olivopontocerebellar atrophy cerebellar cortex. Brain Research, 523:309-312, 1990. 15. Merritt, Houston. A Textbook of Neurology. Lea and Febiger, Philadelphia. 1967 16. Nakazato, Y., Yamazaki, H., Hirato, J. et. al. Oligodendroglial microtubular tangles in olivopontocerebellar atrophy. Journal of Neuropathology and Experimental Neurology, 49:521-530, 1990.

Sure Things

Gangyi Wu Mark Scamahorn Eng 110, March 15, 2012 Desperate to survival How can a big brother who loses his parents in a short period of time survive? How is it possible for him to take care of his little brother at the same time? In A Heartbreaking Work of Staggering Genius, the author Dave Eggers describes a long dialogue between him and his brother Toph. In fact, the dialogue is not happening in the real world; instead, it is a â€Å"me and I† dialogue. Dave talks about his long day in the beginning of this dialogue, while â€Å"Toph† extends the conversation to the discussion of Dave’s inner being.Actually Dave is analyzing his behavior with respect to Toph. From the dialogue, we can tell Dave is desperate and is eager to have a normal life with Toph. Dave’s dialogue with â€Å"Toph’ shows Dave is aggressive. Dave is trying to escape the past and use moral authority to condemn other for the purpose of building himself up. Dave is trying to run a way from the past guilt. The guilty feelings make Dave stay away from the past. â€Å"Toph† says, â€Å"You’re completely paralyzed with guilt about relating all this in the first place, especially the stuff earlier on. †(115).The past was horrible for Dave. He suffered a lot, he lost his parents, and more importantly, his family. He is afraid to remember his family, because he is afraid that those painful memories will haunt after him. The guilt, as â€Å"Toph† describes, constrains him. Dave feels guilty for his parents’ death. The â€Å"family† area in his brain is a forbidden zone. He preserves this area carefully in order to avoid the potential harm coming from the heartrending stories. Otherwise, these areas may drive him ballistic. As a result, Dave tries many ways to escape the guilt.At the very beginning of the conversation, Dave and â€Å"Toph† are talking about their long day. Dave argues that â€Å"this is a much pedestri an day than most†, because â€Å"this is just a caricature†¦ the skeleton†¦Ã¢â‚¬ (115) Toph says: â€Å"you’re†¦. doing little tricks, out of frustration. †(115). From this conversation, we can see that Dave is trying to make things look fake; he does not want things to get a hold of him, especially the guilty feelings. Instead of manipulating the old memories into â€Å"skeleton† and â€Å"caricature† he would rather treat them as his own real experience.He is numbing himself out. By discarding all the old things to jump out of the old memories, Dave also wants to have a brand new life with Toph. â€Å"Toph† says, â€Å"you can toss away all the old rules†¦ and for all your bluster you end up maintaining most of their customs. †(116). He is attempting to leave away from the rules in his old family; he wants to dominate his own rule and create a new home rule. He blusters and struggles. He is desperate! No matter how hard Dave tries, he fails, and all the failures gradually lead him to the edge of collapse.Dave becomes an aggressive man, because he is over sensitive about the potential harm may happen to Toph. â€Å"Toph† recounts a scene between Dave and a friend, Marny. Dave is irritated about Toph’s ignorance’s to call, after waiting for Toph to return home. Marny exhorts Dave not to be harsh but Dave wraths immediately, â€Å"you think you have a say in something like that, just because I am young. †(116) Apparently he is harsh to Toph and now he is mean to his best friend. Marny is showing him kindness whereas Dave attacks her simply because she doubts what he is doing.In this moment, Dave already becomes extremely sensitive. He regards himself as Toph’s mother, â€Å"you would never contradict some forty-year-old mother, would you? † (116) He is a forty-year-old â€Å"mother† who is old enough to have authority over Toph; Dave believes h e has the competence to take care of Toph, and at the mean time he is doing a good parenting job. Therefore, no one can challenge his authority. Consequently Dave overly defends the leadership that he has over the new family. No one can judge an old â€Å"mother†. He is as bossy as an old â€Å"mother† holding the decision making power in his mind.Dave describes his attitude to those potential enemies from â€Å"Toph’s† words, â€Å"You’ll picture all manners of murders in my defense. Your visions will be vivid and horrifically violent†¦Ã¢â‚¬  (117) Dave would like to punish his â€Å"enemies† in his own mind with weapons like a baseball bat. Dave values Toph the most in his heart, and anyone who dares to harm Toph should pay a high price. Dave will punish them as fierce as he can. Paragraph indicates that Dave lacks the sense of safety. Inside his imagination, outsiders always want to dig out his family’s scars and judge him a nd Toph.He desires to beat every enemy down before they appear, so that no one could harm them. He tries to condemn others by using his moral authority in order to gain confidence about life. Toph says, â€Å"You finally have the moral authority you’ve carved†¦And now your moral authority is doubled, tripled. And you use it any way you need to. † (118) The moral authority is the weapon Dave uses to intimidate others. For him it is a shield that protects him from being humiliated, since he is morally superior to others. This is exactly what Toph infers about his authority, â€Å"because it increases your leverage with other people. (119) As a result, Dave can judge others without getting criticism back. In the incomplete family, Dave and Toph are weak. However with the moral authority, he can rule over others; no one will have a judgment about his family, or Toph. He even judges his twenty-nine years old girl friend, â€Å"you’ll make this poor woman feel like a leper†¦ you want her to fell like a pariah, like a lower form of life†¦ what your feel anyone tethered to any addiction is. † (118) â€Å"Leper† and â€Å"pariah† are insulting words that a normal person would not use to criticize a smoking woman.By looking down on others and saying those insulting words, Dave is attempting to gain self-esteem. His behaviors make himself look like a superior. Although the people are living better than Dave, he refuses to accept reality. What Dave wants is to create a favorable family environment for Toph, to give him new home. In this family he is a father, a mother, a big brother and an orphan without parents. Dave is attempting pull himself out of the old and painful memories. On the other hand, he is shouldering the responsibilities of Toph.He talks to the imaginary Toph to cure himself with an â€Å"open heart surgery†. Toph is an illusion of real Toph in his heart. There two brothers are having a coun seling session together indirectly. Dave loves Toph. He is playing his role as a protector. He wants to protect Toph from the people outside their house, to keep Toph from other people’s judgments. The only reason Dave becomes a desperate and pretended guardian is to become strong enough to stand up for Toph’s protection. Work Cited Eggers, Dave. A heartbreaking Work of Staggering Genius, New York. Vintage Books. 2000. 114-120. Print.

What Does It Mean to Make a Claim During an Argument

Claims backed by reasons that are supported by evidence are called arguments. To win an argument, you first have to make a claim that is more than just an assertion. You use critical thinking skills and argue your case using claims, reason, and evidence. In rhetoric  and argumentation, a claim  is an arguable statement—an idea that a rhetor (a speaker or writer) asks an audience to accept. Persuasive Claims Generally speaking, there are three primary types of claims in an argument, also called persuasive claims: Claims of fact assert that something is true or not true.Claims of value assert that something is good or bad, or more or less desirable.Claims of policy assert that one course of action is superior to another. A persuasive claim in an opinion, idea, or assertion. In rational arguments, all three types of claims must be supported by evidence. Jason Del Gandio, in the book, Rhetoric for Radicals, gives these examples of persuasive claims in an argument: I think we should have universal health care.I believe the government is corrupt.We need a revolution. Gandio explains that these claims make sense, but they need to be backed up with evidence and reasoning. Identifying Claims The University of Washington says a claim persuades, argues, convinces, proves, or provocatively suggests something to a reader who may or may not initially agree with you. A claim is more than an opinion but it is less than a universally agreed upon truth, such as The sky is blue or Birds fly in the sky. An academic claim—a claim you make in an argument—is considered debatable or up for inquiry. James Jasinski explains in Argument: Sourcebook on Rhetoric that a claim expresses a specific position on some doubtful or controversial issue that the arguer wants the audience to accept. A claim is not, then, an opinion, such as I think Twinkies are delicious. But if you took that same sentence and recrafted it into an arguable statement, you could create a claim, such as Twinkies and other sugary, processed foods can make you fat. Not everyone might agree with your claim, but you would be able to use scientific and medical evidence (such as studies showing that sugary processed foods lead to weight gain and other health problems) to support your claim. Types of Claims You can further break claims in an argument into four basic types, says Mesa Community College: Claims of fact or definition: Particularly in this day and age, people disagree on hitherto commonly accepted facts. A claim of fact or definition might be that grades do not accurately measure student progress or lie detector tests are inaccurate. Traditionally, grades have been the common measure of student success, but you could argue that they do not really represent a students true abilities. And lie detector tests were at one point thought to provide clear and accurate evidence, but you could use facts to argue that they can be unreliable. Claims About Cause and Effect: This type of claim argues that given causes lead to specific effects, such as watching too much television when young leads to obesity or poor school performance. To make this claim, you would have to show evidence (scientific studies, for example) that show television leads to these outcomes. Another debatable cause-and-effect claim would be that video games that depict violence lead to real violence. Claims About Solutions or Policies: This kind of claim might argue that because the healthcare system does not adequately assist Americans (you would argue that this is a fact), it should be reformed (you argue for the solution/policy), says Mesa Community College. Claims About Value: This type of claim might be the trickiest to argue because you are trying to prove that one thing is better or superior to another. For example, you might claim that people who are blind or deaf have a unique culture of blindness or deafness. You could support either argument by researching and presenting facts that these two areas of disability do indeed have unique cultures and communities.